What Chonluten Is
Chonluten is a synthetic tripeptide, Thr-Glu-Asp (TED), classified within the peptide bioregulator family as associated with bronchial mucosa and respiratory epithelium.
It is one of only two members of the family built on a threonine N-terminus; the rest of the catalog is dominated by lysine- and alanine-initiated sequences. That structural difference is real and verifiable, and it is about as far as verifiable statements about this compound go.
Research use only. Supplied for laboratory research. Not for human or veterinary use. No marketing authorisation exists in any jurisdiction and no therapeutic claim is made.
A Note on the Structural Record
Accuracy about structure is the minimum a supplier owes a researcher, so this is worth documenting: our own catalog previously carried a molecular formula for Chonluten that did not correspond to the Thr-Glu-Asp sequence. It has been corrected.
The correct values, confirmed against PubChem CID 145458042 and by independent calculation from the constituent residues, are C13H21N3O9 at 363.32 g/mol. If you sourced material against the earlier figure, verify the certificate of analysis for the batch you hold.
What the Published Literature Contains
No PubMed-indexed study names Chonluten in its title. There is no compound-specific work establishing an effect on respiratory epithelium, a mechanism specific to Thr-Glu-Asp, a safety profile, or an amount for any species.
The literature commonly cited alongside this compound is class-level: peptide regulation of gene expression (PMID 34834147), short peptides regulating gene expression (PMID 27909961), and peptides regulating proliferative and inflammatory pathways in a monocyte/macrophage cell line (Avolio et al., Int J Mol Sci 2022, PMID 35408963).
These describe the family. None is a study of TED, and the respiratory association attributed to Chonluten comes from the family's own classification scheme rather than from a published experiment on this sequence.
Why the Gap Is Worth Knowing
The absence of literature is not evidence that the compound is inert. It is evidence that no one has published a test. For a researcher, that distinction determines what the compound is good for: it cannot serve as a positive control or a benchmark, but it is a legitimate subject if the question is characterising an unstudied sequence within a family that has a stated mechanistic hypothesis.
Structure and Handling
- Sequence. Thr-Glu-Asp (TED), tripeptide.
- Formula. C13H21N3O9, 363.32 g/mol.
- Form. Lyophilised powder, ≥98% purity, third-party certificate of analysis per batch.
- Storage. Sealed vial at −20 °C, protected from light; reconstituted solution at 2–8 °C.
- Reconstitution. Bacteriostatic water down the vial wall, never onto the powder cake. Do not shake. See the reconstitution calculator.
Related Compounds
Bronchogen (Ala-Glu-Asp-Leu) carries the same respiratory association within the family and has one paper naming it. For compounds with substantive published work see Vilon, Pancragen and Epithalon. The full family sits on our bioregulator overview.