What Ovagen Is
Ovagen is a synthetic tripeptide, Glu-Asp-Leu, classified within the peptide bioregulator family as hepatic-associated.
Ovagen occupies an unusual position. The tripeptide Glu-Asp-Leu is a real, catalogued chemical entity — it resolves to PubChem CID 444128, C15H25N3O8, 375.37 g/mol, matching our catalog record. What does not exist is any published study of it under the name Ovagen.
Research use only. Supplied for laboratory research. Not for human or veterinary use. No marketing authorisation exists in any jurisdiction and no therapeutic claim is made.
Known Sequence, Unstudied Trade Name
This distinction matters more than it first appears. A compound can be structurally well defined and biologically uncharacterised at the same time, and Glu-Asp-Leu is that case: the molecule is unambiguous, while its proposed hepatic role rests entirely on the family's classification scheme rather than on an experiment.
A PubMed search returns no study whose title names Ovagen. No published work establishes an effect on liver function, lipid metabolism, or any other endpoint attributed to it, and no amount is established for any species.
The Class-Level Literature, and Its Limits
The papers usually cited around this compound concern the family: the systematic review of peptide regulation of gene expression (Khavinson et al., Molecules 2021, PMID 34834147) and peptide regulation of cell differentiation (Khavinson et al., Stem Cell Rev Rep 2020, PMID 31808038).
Both are about short peptides as a class. Neither tested Glu-Asp-Leu. Presenting them as support for hepatic claims about Ovagen would attribute to one sequence what was argued about many.
Worth noting for anyone comparing within the family: Livagen (Lys-Glu-Asp-Ala) carries the same hepatic association and does have papers naming it directly. If hepatic association is the reason for the interest, Livagen is the better-documented starting point.
Structure and Handling
- Sequence. Glu-Asp-Leu, tripeptide.
- Formula. C15H25N3O8, 375.37 g/mol (PubChem CID 444128).
- Form. Lyophilised powder, ≥98% purity, third-party certificate of analysis per batch.
- Storage. Sealed vial at −20 °C, protected from light; reconstituted solution at 2–8 °C.
- Reconstitution. Bacteriostatic water down the vial wall, never onto the powder cake. Do not shake. See the reconstitution calculator.
Where to Look Instead
For compounds in this family with studies naming them: Vilon (Lys-Glu), Pancragen (Lys-Glu-Asp-Trp), Epithalon (Ala-Glu-Asp-Gly), Thymalin and Livagen. The full catalog with the evidence position for each is on our bioregulator overview.