≥98%HPLC Purity
COAIncluded
USAShipped
PEG-MGF Peptide
PEGylated form of Mechano Growth Factor with enhanced bioavailability and extended half-life. Studied for skeletal muscle hypertrophy, satellite cell activation, and recovery research.
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Quick Facts
| SKU | PEGMGF-001 |
|---|---|
| Purity | ≥98% |
| Physical Form | Lyophilized Powder |
| Storage | Store at -20°C |
What is PEG-MGF?
PEG-MGF (PEGylated Mechano Growth Factor) is a splice variant of IGF-1 with polyethylene glycol modification. The PEG moiety extends the biological half-life from minutes to several hours by reducing renal clearance and proteolytic degradation. MGF (IGF-1Ec) is expressed in response to mechanical stress in muscle tissue and activates satellite cells for muscle repair and hypertrophy.
Mechanism of Action
MGF activates muscle satellite cells (muscle stem cells) via the IGF-1R pathway, promoting their proliferation and fusion into existing myofibers. Unlike systemic IGF-1, MGF acts locally at the site of mechanical damage. The PEG modification allows systemic research administration with sustained satellite cell activation across multiple muscle groups.
Frequently Asked Questions
PEG-MGF vs MGF vs IGF-1 LR3?
MGF is a local muscle growth factor active for minutes. PEG-MGF extends this to hours via PEGylation. IGF-1 LR3 has systemic effects on overall growth. PEG-MGF specifically targets satellite cell activation for muscle repair.
For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.
