IGF-1 DES Peptide

Des(1-3)IGF-1 is a truncated IGF-1 variant lacking the first 3 N-terminal amino acids. Enhanced bioactivity due to reduced IGFBP binding.

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Quick Facts

SKUACR-IGFDES
CAS Number112603-35-7
Molecular Weight7365.00 g/mol
Sequence67-amino acid truncated IGF-1
Purity≥98%
Physical FormLyophilized Powder
StorageStore at -20°C

What is IGF-1 DES?

IGF-1 DES (Des(1-3) IGF-1) is a truncated form of IGF-1 missing the first 3 amino acids. This modification eliminates binding to IGFBPs (IGF Binding Proteins), resulting in a compound approximately 10x more potent than full-length IGF-1 because 100% of the peptide remains bioavailable for receptor activation.

Frequently Asked Questions

IGF-1 DES vs IGF-1 LR3?

IGF-1 DES lacks 3 N-terminal amino acids, making it 10x more potent but shorter-acting. IGF-1 LR3 has an extended half-life due to reduced IGFBP binding but is less potent per molecule.

For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.