≥99%HPLC Purity
COAIncluded
USAShipped
MGF (Mechano Growth Factor) Peptide
Splice variant of IGF-1 expressed in response to mechanical stimulation. 24-amino acid peptide studied for muscle biology research.
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Quick Facts
| SKU | ACR-MGF |
|---|---|
| CAS Number | 62031-54-3 |
| Molecular Weight | 2867.14 g/mol |
| Sequence | 24-amino acid IGF-1 splice variant |
| Purity | ≥98% |
| Physical Form | Lyophilized Powder |
| Storage | Store at -20°C |
What is MGF?
Mechano Growth Factor (MGF) is a splice variant of IGF-1 produced in response to mechanical stress on muscle tissue. When the IGF-1 gene is activated by mechanical loading, it undergoes alternative splicing to produce MGF (IGF-1Ec in humans, IGF-1Eb in rodents) rather than the liver-type systemic IGF-1Ea isoform.
The active C-terminal E-domain peptide of MGF consists of 24 amino acids and is responsible for its unique biological activity. Published research has investigated MGF expression in exercised and damaged muscle tissue and its role in satellite cell activation and proliferation.
For laboratory research use only.
Frequently Asked Questions
What is MGF?
MGF (Mechano Growth Factor) is a splice variant of IGF-1 produced by mechanical muscle loading. The active 24-amino acid C-terminal peptide has been studied for satellite cell activation. It differs from systemic IGF-1 in tissue specificity. For research use only.
For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.
