Nonapeptide-1 Peptide

Alpha-MSH (melanocyte-stimulating hormone) antagonist researched for melanin regulation. Studied for inhibiting melanogenesis and skin pigmentation modulation.

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Quick Facts

SKUNONA-001
Purity≥98%
Physical FormLyophilized Powder
StorageStore at -20°C

What is Nonapeptide-1?

Nonapeptide-1 is a competitive antagonist of alpha-MSH at the MC1 receptor on melanocytes. By blocking MC1R activation, it reduces cAMP signaling and MITF-mediated transcription of tyrosinase, TRP-1, and TRP-2, the key enzymes in melanin biosynthesis.

Frequently Asked Questions

How does Nonapeptide-1 reduce melanin?

It competes with alpha-MSH for binding at MC1R on melanocytes. By blocking this receptor, it prevents the cAMP/MITF signaling cascade that activates melanin-producing enzymes (tyrosinase, TRP-1, TRP-2).

For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.