≥99%HPLC Purity
COAIncluded
USAShipped
LL-37 Peptide
Human cathelicidin antimicrobial peptide. A 37-amino acid peptide studied in innate immunity and host defense peptide research.
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Quick Facts
| SKU | ACR-LL37 |
|---|---|
| CAS Number | 154947-66-7 |
| Molecular Weight | 4493.33 g/mol |
| Sequence | 37-amino acid cathelicidin |
| Purity | ≥95% |
| Physical Form | Lyophilized Powder |
| Storage | Store at -20°C |
What is LL-37?
LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide derived from the C-terminus of the 18-kDa hCAP18 precursor protein. Its name reflects its 37-amino acid length and the two leucine residues at its N-terminus.
LL-37 adopts an amphipathic alpha-helical structure that enables it to interact with bacterial membranes. Published research has documented its broad-spectrum antimicrobial activity against gram-positive bacteria, gram-negative bacteria, fungi, and enveloped viruses, as well as its immunomodulatory functions beyond direct antimicrobial action.
For laboratory research use only.
Frequently Asked Questions
What is LL-37?
LL-37 is the only human cathelicidin — a 37-amino acid cationic antimicrobial peptide derived from the hCAP18 precursor. It forms amphipathic helices that interact with microbial membranes and also has immunomodulatory signaling functions. For research use only.
For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.