Kisspeptin-10 Peptide

C-terminal decapeptide fragment of kisspeptin. Studied for its activation of the GPR54 (KISS1R) receptor in endocrine research.

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Quick Facts

SKUACR-KISS10
CAS Number374675-21-5
Molecular Weight1302.42 g/mol
SequenceTyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Purity≥99%
Physical FormLyophilized Powder
StorageStore at -20°C

What is Kisspeptin-10?

Kisspeptin-10 is a synthetic decapeptide corresponding to the C-terminal 10 amino acids (112-121) of the kisspeptin family, encoded by the KISS1 gene. Kisspeptins are the endogenous ligands for the GPR54 (KISS1R) receptor and are considered the most potent upstream activators of the GnRH neuronal system. The discovery of kisspeptin signaling in 2003 fundamentally changed understanding of reproductive neuroendocrinology. Inactivating mutations in KISS1R cause hypogonadotropic hypogonadism, demonstrating the essential role of this pathway in GnRH regulation. For laboratory research use only.

Frequently Asked Questions

What is Kisspeptin-10?

Kisspeptin-10 is a decapeptide that activates the GPR54/KISS1R receptor, the most potent upstream activator of GnRH neurons. It is a critical regulator of the reproductive endocrine axis discovered in 2003. For research use only.

For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.