≥98%HPLC Purity
COAIncluded
USAShipped
Gonadorelin Peptide
Synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH). Used in receptor binding and signaling studies.
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| SKU | ACR-GNRH |
|---|---|
| CAS Number | 33515-09-2 |
| Molecular Weight | 1182.29 g/mol |
| Sequence | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 |
| Purity | ≥98% |
| Physical Form | Lyophilized Powder |
| Storage | Store at -20°C |
What is Gonadorelin?
Gonadorelin is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH). Its sequence is pyroGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2. GnRH is the master regulator of the reproductive endocrine axis, secreted in pulsatile fashion from hypothalamic neurons.
Gonadorelin binds to the GnRH receptor (GnRHR), a G-protein coupled receptor on anterior pituitary gonadotroph cells. Pulsatile activation stimulates LH and FSH secretion, while continuous activation causes receptor desensitization and gonadotropin suppression.
For laboratory research use only.
Frequently Asked Questions
What is Gonadorelin?
Gonadorelin is synthetic GnRH (gonadotropin-releasing hormone), a 10-amino acid peptide that controls LH and FSH secretion. Pulsatile administration stimulates gonadotropin release, while continuous exposure causes receptor desensitization. For research use only.
For laboratory and research use only. Not intended for human or animal consumption. All product information is derived from published preclinical research and does not constitute medical advice or claims.