SLU-PP-332
Also referenced as SLU PP 332
Small-molecule pan-agonist of the estrogen-related receptors (ERRα, ERRβ, ERRγ), studied as an exercise mimetic.
Available forms
Each form is a separate product with its own dosing, handling and price. The research summary below applies to the compound itself.
Compound data
| Molecular formula | C27H25N3O4S |
|---|---|
| Molecular weight | 487.57 g/mol |
| CAS number | 2410279-67-7 |
| Sequence | N/A (small molecule) |
Mechanism
SLU-PP-332 is a synthetic small molecule that acts as an agonist of the estrogen-related receptors (ERRs) — specifically ERRα, ERRβ and ERRγ. These orphan nuclear receptors are described in the literature as regulators of mitochondrial biogenesis and cellular energy metabolism.
Published preclinical work has investigated its capacity to activate ERR-dependent transcriptional programs, including genes involved in oxidative phosphorylation and fatty acid oxidation.
Why it exists in more than one form
SLU-PP-332 is a small molecule rather than a peptide. Peptides are cleaved by gastric and intestinal proteases, which is why most are supplied as lyophilized powder for reconstitution. Small molecules of this class are not substrates for those enzymes, so an oral capsule presentation is feasible alongside the vial.
Research Use Statement
For Research Use Only. The compounds referenced on this page are supplied for laboratory research and in-vitro experimental use. They are not for human or veterinary use, and are not a drug, supplement or food.
Nothing on this page is FDA approved for any indication, is not intended to diagnose, treat, cure or prevent any disease, and does not constitute medical advice.