Peptide Research Guides: BPC-157, TB-500, GHK-Cu

Vesilut (Lys-Glu-Asp): Urinary Tract Tissue Bioregulator Research

Vesilut is a synthetic tripeptide with the sequence Lys-Glu-Asp (KED) and a molecular weight of 390.39 g/mol, developed within the Khavinson bioregulator family as a tissue-specific research compound targeting urinary tract and bladder tissue. This article examines its proposed molecular mechanisms, situates it within the broader KED peptide nomenclature debate, and reviews the available preclinical evidence.

Jul 31, 2026 · 14 min read

["Khavinson Peptide Bioregulators" "Urinary Tract Research" "Epigenetic Mechanisms"

Pancragen (Lys-Glu-Asp-Trp): Pancreatic Beta-Cell and Insulin Regulation Research

Pancragen (KEDW) is a tetrapeptide bioregulator derived from pancreatic tissue, investigated in preclinical models for its apparent role in beta-cell gene expression, insulin secretion dynamics, and metabolic homeostasis during aging. This article examines the molecular architecture, proposed mechanisms, and comparative context within the Khavinson peptide bioregulator family.

Jul 31, 2026 · 13 min read

["Peptide Bioregulators" "Pancreatic Research" "Khavinson Peptides"

Livagen (Lys-Glu-Asp-Ala): Hepatic Bioregulator and Chromatin Decondensation Research

Livagen is a tetrapeptide bioregulator (KEDA, MW 475.50 g/mol) derived from liver tissue, studied for its capacity to induce chromatin decondensation and restore hepatic gene expression patterns — making it a central model compound in Khavinson's peptide-DNA hypothesis.

Jul 31, 2026 · 12 min read

["Khavinson Peptide Bioregulators" "Chromatin Decondensation" "Hepatic Bioregulation"

Chonluten (Thr-Glu-Asp): Respiratory Mucosa and Immune Modulation Research

Chonluten (Thr-Glu-Asp) is a tripeptide bioregulator developed within the Khavinson peptide framework, demonstrating tissue-selective activity in bronchial mucosa and respiratory epithelium. Research suggests it modulates local immune signaling and epithelial gene expression through mechanisms distinct from those of Bronchogen and other pulmonary-targeting short peptides.

Jul 31, 2026 · 12 min read

["Khavinson Peptide Bioregulators" "Respiratory Research" "Mucosal Immunology"

Ovagen (Glu-Asp-Leu): Tissue Specificity and Bioregulator Research

Ovagen is a synthetic tripeptide (Glu-Asp-Leu) from Khavinson's bioregulator family, investigated in research models for its tissue-specific gene-regulatory activity and role in lipid metabolism and cellular aging. This article examines its molecular identity, proposed mechanisms, and position within the broader Khavinson peptide framework.

Jul 31, 2026 · 12 min read

["Khavinson peptide bioregulators" "Ovagen EDL tripeptide" "tissue-specific gene regulation"

Cortagen (Ala-Glu-Asp-Pro): Cortical Neuroprotection Bioregulator Research

Cortagen (AEDP) is a tetrapeptide bioregulator developed by Vladimir Khavinson with documented activity in cerebral cortex tissue models, appearing to modulate gene expression patterns associated with neuronal survival, synaptic integrity, and age-related cortical decline in experimental settings.

Jul 31, 2026 · 13 min read

["Khavinson peptide bioregulators" "neuroprotection research" "cerebral cortex"

Vesugen (Lys-Glu-Asp): Vascular Endothelium Bioregulator Research

Vesugen (KED) is a tripeptide bioregulator developed by Vladimir Khavinson's research group with a molecular weight of 390.39 g/mol, investigated for its role in vascular endothelium gene expression regulation and cardiovascular tissue homeostasis. This article reviews the structural basis, molecular mechanisms, and comparative position of Vesugen within the Khavinson peptide bioregulator family.

Jul 31, 2026 · 12 min read

["Khavinson peptide bioregulators" "vascular endothelium research" "epigenetic bioregulation"

Cardiogen (Ala-Glu-Asp-Arg): Myocardial Function Bioregulator Research

Cardiogen (AEDR) is a tetrapeptide bioregulator developed within the Khavinson framework, investigated for its tissue-specific effects on myocardial gene expression and cardiac function normalization in aging research models. This article examines its molecular structure, proposed mechanisms, and the current state and limitations of available evidence.

Jul 31, 2026 · 13 min read

["Khavinson peptide bioregulators" "cardiac aging research" "myocardial function"

Bronchogen (Ala-Glu-Asp-Leu): Respiratory Epithelium Bioregulator Research

Bronchogen is a tetrapeptide bioregulator (Ala-Glu-Asp-Leu, MW 460.48 g/mol) developed within the Khavinson peptide framework, with research suggesting tissue-specific epigenetic activity directed at bronchial and respiratory epithelium. This article examines its molecular sequence, proposed mechanism, comparative position within the bioregulator family, and laboratory handling protocols.

Jul 31, 2026 · 13 min read

["Khavinson Peptide Bioregulators" "Respiratory Research" "Bronchial Epithelium"

Prostamax (Lys-Glu-Asp-Pro): Prostate Tissue Bioregulator Research

Prostamax is a tetrapeptide bioregulator with the sequence Lys-Glu-Asp-Pro (KEDP) and a molecular weight of 487.51 g/mol, developed within the Khavinson peptide framework to investigate tissue-specific gene expression normalization in aging prostate models. This article examines its molecular architecture, proposed mechanism of action, and the experimental designs underlying available research.

Jul 31, 2026 · 13 min read

["Khavinson peptide bioregulators" "Prostate tissue research" "Tetrapeptide mechanisms"

Vilon (Lys-Glu): Thymic Dipeptide Research in T-Cell and Immune Regulation

Vilon (Lys-Glu) is the smallest member of the Khavinson peptide bioregulator family, with a molecular weight of 275.30 g/mol. Research across thymic aging models and T-cell signaling cascades positions this dipeptide as a molecularly precise tool for studying immune senescence and thymus-dependent lymphocyte regulation.

Jul 31, 2026 · 13 min read

["Khavinson peptide bioregulators" "thymic peptides" "immune regulation research"

Testagen (Lys-Glu-Asp-Gly): Leydig Cell Function and Steroidogenic Research

Testagen (KEDG) is a tetrapeptide bioregulator developed within the Khavinson framework, investigated for its capacity to modulate gene expression in Leydig cells and support steroidogenic enzyme activity in aging testicular models. This article examines its molecular architecture, proposed mechanisms, and position within the broader family of short peptide bioregulators.

Jul 31, 2026 · 14 min read

["Khavinson peptide bioregulators" "Testagen KEDG" "Leydig cell research"

Research Articles